Towards multiple readout application of plasmonic arrays

• Dana Cialla,
• Karina Weber,
• René Böhme,
• Uwe Hübner,
• Henrik Schneidewind,
• Matthias Zeisberger,
• Roland Mattheis,
• Robert Möller and
• Jürgen Popp

Beilstein J. Nanotechnol. 2011, 2, 501–508, doi:10.3762/bjnano.2.54

• readout; plasmonic array; surface-enhanced fluorescence (SEF); surface-enhanced Raman spectroscopy (SERS); Introduction Fluorescence spectroscopy and microscopy is one of the most important analytical techniques in the life sciences and medicine. Due to its extreme sensitivity, fluorescence allows

• advantages of both fluorescence and SERS spectroscopy in a single sensor platform, the goal of the work presented here is the development and application of an innovative nanostructured surface that will allow both detection schemes. Thus, several requirements must be fulfilled by the plasmonic array: (1

• detecting both fluorescence and SERS signals through a single plasmonic array, since the optimum distance between the (fluorescent) molecules and the metallic surface, for gaining the maximum signal intensity, is different in the two cases. The most efficient SERS enhancement is achieved for molecules